Raws li qhov zoo tib yam hollow capsule shells muaj kev txhawj xeeb, cov khoom siv matrix feem ntau yog gelatin thiab hypromellose (HPMC).
| gelatin capsule plhaub | HPMC capsule plhaub | |
| qeb | tsiaj-derived capsule shells | Plant-Based Capsule Plhaub |
| cov khoom tseem ceeb | Gelatin (los ntawm tsiaj pob txha, tawv nqaij) ntxiv dej | Hypromellose (los ntawm paj rwb linters, ntoo pulp) ntxiv rau dej |
| Cov txheej txheem ntau lawm | Gelatin tau txais los ntawm cov ntaub so ntswg tsiaj los ntawm cov txheej txheem xws li degreasing thiab demineralization nyob rau hauv cov xwm txheej tsim nyog. Gelatin lossis HPMC yog yaj hauv dej ntawm qhov ntsuas kub kom tsim tau cov tshuaj, cov pwm tshwj xeeb yog muab tso rau hauv cov tshuaj kub, thiab cov tshuaj gels los ua ib zaj duab xis thaum txias, thiab tom qab ntawd tom qab ua tiav xws li ziab thiab polishing. | |
| dej cov ntsiab lus | 12.5 ~ 17.5 feem pua | 4% ~ 7 feem pua |
| Solubility | swells hauv dej txias ntawm 25 degree, tsis yaj | Dissolve maj mam nyob rau hauv dej txias ntawm 25 degree |
| crumbly | tsis muaj | Tsawg dua 5 ntawm 50 |
| kev nyab xeeb | Muaj kev nyab xeeb thiab txhim khu kev qha, nws muaj nyob rau hauv pharmacopoeia ntawm ntau lub teb chaws | Muaj kev pheej hmoo ntawm ntau cov tshuaj tua kab mob thiab kab mob nyuj vwm |
Pom tseeb qhov tsis zoo ntawm gelatin capsules:
(1) Vim tias cov ntsiab lus dej nyob nruab nrab ntawm 12.5 feem pua thiab 17.5 feem pua , nws yooj yim poob dej thaum lub sij hawm muab tso rau hauv cov txheej txheem, ua rau tsis zoo toughness thiab softening vim absorbed noo noo. Qhov kub thiab av noo ntawm qhov chaw cia khoom (15 ~ 25 degree, RH feem pua 35 ~ 65 feem pua) thiab cov khoom ntim yuav tsum siab dua.
(2) Lub ntsiab tseem ceeb ntawm gelatin capsules yog gelatin (protein), uas dhau los ntawm kev sib txuas cov tshuaj tiv thaiv thaum ntsib cov amino acids, aldehydes, txo cov suab thaj thiab cov vitamins.
Txhawm rau kov yeej qhov teeb meem kev ruaj ntseg ntawm gelatin capsules, HPMC capsules tau tsim, uas yog tsim los ntawm hypromellose thiab dej, thiab qee zaum muaj cov khoom ntxiv xws li plasticizers, surfactants, gelling agents, dispersing agents, flavoring agents, preservatives and sweetening agents, thiab kuj tseem yuav muaj cov tshuaj opacifying, cov tshuaj pleev xim thiab/los yog cov kev pab ua.
